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The FDA has approved Gardasil and Gardasil 9 for use in females ages 9 through 26 for the prevention of HPV-caused cervical, vulvar, vaginal, and anal cancers; precancerous cervical, vulvar, vaginal, and anal lesions; and genital warts.Gardasil and Gardasil 9 are also approved for use in males for the prevention of HPV-caused anal cancer, precancerous anal lesions, and genital warts.Gardasil also prevents infection with HPV types 6 and 11, which cause 90% of genital warts (17).

The vaccines do not prevent other sexually transmitted diseases, nor do they treat existing HPV infections or HPV-caused disease.

Because the infection is so common, most people get HPV infections shortly after becoming sexually active for the first time (13, 14). Someone can have an HPV infection even if they have no symptoms and their only sexual contact with an HPV-infected person happened many years ago.

HPV vaccination can reduce the risk of infection by the HPV types targeted by the vaccine.

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Most high-risk HPV infections occur without any symptoms, go away within 1 to 2 years, and do not cause cancer.

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